Boston to Rome & Return from Naples

Multi-City Flights to Experience Ancient Rome & the Amalfi Coast

Why Book Multi-City: Rome to Naples?

The ultimate Southern Italy journey from ancient ruins to coastal paradise

Arrive in Rome (FCO)

Fly from Boston (BOS) to Rome Fiumicino Airport - gateway to the Eternal City

High-Speed Train to Naples

Travel by Frecciarossa through the Italian countryside in about 1 hour 10 minutes

Return from Naples (NAP)

Fly back to Boston from Naples International Airport after exploring the Amalfi Coast

Search Multi-City Flights
Boston to Rome and Naples Multi-City Route

Multi-city route: Arrive Rome, Return from Naples

Rome to Naples Ground Transportation

Fast connections to Southern Italy

Frecciarossa High-Speed

  • 1h 10m journey
  • 300 km/h speed
  • WiFi & power outlets
  • From $35 one-way
Recommended

Italo Train

  • 1h 10m journey
  • Luxury seating
  • Onboard cafe
  • From $30 one-way
Great Value

Car Rental

  • 2.5-3 hours drive
  • Stop at Pompeii
  • Scenic Amalfi Drive
  • From $50/day
Most Flexible

Create Your Custom-Made Journey Through Italy

Click the to save items to your wishlist

Where do you want to visit?

Select as many options as you like

Rome, Italy
Rome

The Eternal City with stunning classical ruins and Renaissance art

Naples, Italy
Naples

Vibrant city with the best pizza and gateway to Pompeii

Amalfi Coast, Italy
Amalfi Coast

UNESCO coastline with Positano, Ravello and stunning cliffs

Pompeii, Italy
Pompeii

Ancient Roman city preserved by Vesuvius eruption

Capri, Italy
Capri

Glamorous island with Blue Grotto and stunning views

Sorrento, Italy
Sorrento

Cliffside town with lemon groves and Bay of Naples views

Which type of activities do you enjoy?

Select as many as you like

History
Ancient History

Colosseum, Pompeii and Roman ruins

Beaches
Coastlines & Beaches

Amalfi cliffs and Mediterranean shores

Food
Cuisine & Food Tours

Neapolitan pizza, seafood and limoncello

Art
Art & Architecture

Vatican Museums and Baroque churches

Islands
Island Hopping

Capri, Ischia and Procida day trips

Wine
Wine & Vineyards

Campanian wines and volcanic terroir

What are your travel plans?
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Popular Hotels in Rome

Elegant stays in the heart of the Eternal City

Hotel Hassler Roma
Hotel Hassler Roma

Rome, Spanish Steps

5-Star Luxury

Iconic luxury hotel atop the Spanish Steps with panoramic views

From $650/night
Hotel Eden Rome
Hotel Eden, Dorchester Collection

Rome, Via Veneto

5-Star

Rooftop restaurant with stunning city and Vatican views

From $580/night
Hotel de Russie
Hotel de Russie

Rome, Piazza del Popolo

5-Star

Elegant Rocco Forte hotel with stunning secret garden

From $550/night
View All Rome Hotels

Popular Hotels on the Amalfi Coast

Stunning cliffside retreats with Mediterranean views

Belmond Hotel Caruso
Belmond Hotel Caruso

Ravello, Amalfi Coast

5-Star Luxury

11th-century palace with infinity pool overlooking the coast

From $950/night
Le Sirenuse
Le Sirenuse

Positano, Amalfi Coast

5-Star Legend

Iconic Positano hotel with Michelin-starred restaurant

From $1,100/night
Grand Hotel Excelsior Vittoria
Grand Hotel Excelsior Vittoria

Sorrento

5-Star Historic

Clifftop estate with private elevator to the sea

From $680/night
View All Amalfi Coast Hotels

Things to Do

  • Colosseum - Ancient Roman amphitheater icon
  • Vatican Museums - World's greatest art collection
  • Pompeii - Ancient city preserved by Vesuvius
  • Amalfi Drive - Scenic coastal road trip
  • Blue Grotto - Famous sea cave in Capri
  • Naples Pizza - Birthplace of margherita pizza

Airlines Flying This Route

BOSBoston
FCORome
NAPNaples
BOSBoston
Book Multi-City Flight *Taxes and surcharges included. Prices may vary.