Flights from Denver to Rome

Discover amazing deals on round trip flights from Denver to Rome. Search, compare, and book the best fares today.

Rome Italy

Flights from Denver to Rome

The Denver to Rome route connects Colorado's Mile High City with Italy's eternal capital. With multiple departures from Denver International Airport (DEN) to Rome Fiumicino (FCO), you'll find plenty of options to explore the ancient wonders, Renaissance art, and world-famous cuisine of Rome.

Pro Tip: Book 6-8 weeks in advance for the best fares. Midweek departures (Tuesday-Thursday) often offer significant savings!

Direct flights available from DEN to FCO
Flight time: 11-12 hours
Best time to visit: April to June, September to October
Round trip from: $529

Popular Hotels in Rome

Handpicked accommodations for an unforgettable Rome experience

Hotel in Rome

Hotel Hassler Roma

Rome, Piazza Trinità dei Monti

Iconic luxury hotel atop the Spanish Steps with panoramic city views

From $450/night

Hotel Eden Rome

Hotel Eden

Rome, Via Ludovisi

Historic luxury hotel with rooftop restaurant overlooking St. Peter's

From $580/night

Rome Cavalieri

Rome Cavalieri, A Waldorf Astoria

Rome, Via Alberto Cadlolo

Hilltop resort with priceless art collection and 3 Michelin-star dining

From $420/night

Search All Rome Hotels

Create Your Custom-Made Journey Through Italy

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Where do you want to visit?

Select as many options as you like

Rome Historic Center

Rome Historic Center

The Colosseum, Roman Forum and ancient ruins

Vatican City

Vatican City

St. Peter's Basilica, Sistine Chapel and Vatican Museums

Trastevere

Trastevere

Charming cobblestone streets and authentic Roman trattorias

Amalfi Coast

Amalfi Coast

UNESCO coastline with Positano, Amalfi and Ravello

Florence

Florence

Renaissance art capital with the Uffizi and Duomo

Pompeii

Pompeii

Ancient Roman city preserved by Vesuvius eruption

Which type of activities do you enjoy?

Select as many as you like

Ancient History

Ancient History

Roman ruins, Colosseum and archaeological wonders

Art Museums

Art & Museums

Vatican Museums, Borghese Gallery and Renaissance masterpieces

Roman Food

Roman Cuisine

Pasta carbonara, cacio e pepe and authentic trattorias

Wine

Wine Tours

Chianti, Frascati and Lazio wine country

Religious Sites

Religious Sites

Vatican, historic churches and sacred monuments

Coastal

Coastal Escapes

Amalfi, Capri and Mediterranean beaches

What are your travel plans?

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Trip Duration

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What would make your vacation special?

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Or call us directly at 1-214-227-6700

Airlines Flying Denver to Rome

Choose from top carriers for your journey

ITA Airways

ITA Airways

American Airlines

American Airlines

Lufthansa

Lufthansa

Air France

Air France

Swiss

Swiss

Other Italy Routes from Denver

Pro Tip: Consider flying into Rome and out of Milan (or vice versa) to see more of Italy without backtracking.

To Milan

Denver to Milan

From New York

From Chicago

From Los Angeles