Flights from Detroit to Prague

Discover amazing deals on round trip flights from Detroit to Prague. Search, compare, and book the best fares today.

Prague Czech Republic

Flights from Detroit to Prague

The Detroit to Prague route connects America's Motor City with one of Europe's most beautiful capitals, the "City of a Hundred Spires." With departures from DTW Detroit Metropolitan Wayne County Airport to Vaclav Havel Airport Prague (PRG), you'll find excellent options to explore Prague Castle, Charles Bridge, the astronomical clock, and the charming cobblestone streets of this fairy-tale city.

Pro Tip: Book 6-8 weeks in advance for the best fares. Midweek departures (Tuesday-Thursday) often offer significant savings!
  • Connecting flights available from DTW to PRG
  • Flight time: 9-10 hours
  • Best time to visit: April to June, September to October
  • Round trip from: $549

Popular Hotels in Prague

Handpicked accommodations for an unforgettable Prague experience

Hotel in Prague
Four Seasons Hotel Prague

Prague, Old Town

5-Star Luxury

Riverside luxury with stunning views of Charles Bridge and Prague Castle

From $380/night
Mandarin Oriental Prague
Mandarin Oriental Prague

Prague, Mala Strana

5-Star Luxury

Former monastery with award-winning spa near Prague Castle

From $420/night
Augustine Prague
Augustine, a Luxury Collection Hotel

Prague, Mala Strana

5-Star Luxury

Converted Augustinian monastery with brewery and beautiful gardens

From $350/night
Search All Prague Hotels

Create Your Custom-Made Journey Through Czech Republic

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Where do you want to visit?
Prague
Prague

City of a Hundred Spires with Charles Bridge and castle

Cesky Krumlov
Cesky Krumlov

Fairytale UNESCO town with 13th-century castle

Karlovy Vary
Karlovy Vary

Elegant spa town with healing hot springs

Brno
Brno

Moravian capital with modernist architecture

Kutna Hora
Kutna Hora

Silver mining town with famous bone church

Pilsen
Pilsen

Birthplace of Pilsner beer with brewery tours

Which type of activities do you enjoy?
Czech Beer
Czech Beer

Pilsner Urquell brewery tours and beer spas

Castles
Bohemian Castles

Prague Castle, Karlstejn and 2000+ castles

Spa
Spa Towns

Karlovy Vary, Marianske Lazne and thermal treatments

Architecture
Gothic Architecture

St Vitus Cathedral, astronomical clock and medieval streets

Music
Classical Music

Opera, concerts and Mozart heritage

Food
Bohemian Cuisine

Svickova, trdelnik and traditional Czech food

What are your travel plans?
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Airlines Flying Detroit to Prague

Choose from top carriers for your journey

Air Canada

Air Canada
American Airlines

American Airlines
Finnair

Finnair
Aer Lingus

Aer Lingus
United Airlines

United Airlines
Lufthansa

Lufthansa

Other European Routes from Detroit

To Hungary
To Poland
To Germany
To Switzerland
DTW Detroit
PRG Prague
Book Round Trip Flight *Taxes and surcharges included. Prices may vary.